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首頁(yè) /診斷試劑 /用藥指導(dǎo)標(biāo)準(zhǔn)品 /他莫昔芬CYP2D6多態(tài)性 /CYP2D6*10 Reference Standard

CYP2D6*10 Reference Standard

CBPA0072

詢 價(jià)
索取COA
產(chǎn)品描述
產(chǎn)品數(shù)據(jù)庫(kù)
Introduction 
Format Genomic DNA
Description CYP2D6, cytochrome P450 family 2 subfamily D member 6, is a member of the cytochrome P450 family of monooxygenases that catalyzes drug metabolism (PMID: 28480783). CYP2D6 variants have been associated with risks of various cancers (PMID: 22994728, PMID: 16550168) and may alter the metabolism of tamoxifen in breast cancer patients.
   
Technical Data
Gene CYP2D6
Mutation Type 1 AA Change: p.S486T
DNA Change: NM_000106.6:c.1457G>C
Chr position (GRCh38): chr22:42126611
Mutation Type 2 AA Change: p.P34S
DNA Change: NM_000106.6:c.100C>T
Chr position (GRCh38): chr22:42130692
Mutation Type 3 AA Change: N/A
DNA Change: NM_000106.6:c.408G>C
Chr position (GRCh38): chr22:42129130
Allelic Frequency 100%
Zygosity Homozygous
   
Product Information
Intended Use Research Use Only
Unit Size 1ug
Concentration Download for COA
Purofication Download for COA
DNA electrophoresis Download for COA
Sanger sequencing

Figure 1. CYP2D6*10 Reference Standard p.S486T

Figure 2. CYP2D6*10 Reference Standard p.P34S

Figure 3. CYP2D6*10 Reference Standard c.408G>C

Storage 2-8°C
Expiry 36 months from the date of manufacture

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診斷標(biāo)準(zhǔn)品聯(lián)系方式: 華東銷售經(jīng)理:15000320447 華北銷售經(jīng)理:18628311252 華南銷售經(jīng)理:13823536064 華中&華西銷售經(jīng)理:18071545918 華中&西南銷售經(jīng)理:13871580511 全國(guó)銷售經(jīng)理:13816461235

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