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首頁 /藥靶模型 /GPCR靶點細(xì)胞 /Class A(Rhodopsin) /CXCR4/CHO

CXCR4/CHO

CBP71358

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I. Background
CXCR4 is a receptor for the C-X-C chemokine SDF-1 (Stromal Cell-Derived Factor 1). It is involved in haematopoiesis 
and cardiac ventricular septum formation, and plays an essential role in vascularization of the gastrointestinal tract, 
cerebellar development and survival of hippocampal-neuron of central nerve system. CXCR4 also acts as a primary 
receptor for some HIV-2 isolates and as a co-receptor with CD4 for HIV-1 X4 viruses.
 
II. Introduction
Host Cell:

CHO

Stability: 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium: 90% FBS+10% DMSO
Culture Medium: F12K+10%FBS+5ug/ml puromycin
Mycoplasma Status: Negative
Storage: Liquid nitrogen immediately upon delivery
Application(s):

Functional assay for CXCR4

Transducer: Gi
 
Ⅲ. Description of Host Cell Line
Organism: Hamster
Tissue: Ovary
Morphology: Epithelial
Growth Properties: Adherent
 
Ⅳ. Representative Data


Figure 1. Recombinant CXCR4/CHO stably expressing CXCR4.

Figure 2. Human CXCR4 antibody effect on CXCR4/CHO-K1 clone 6.

Figure 3. CXCL 12 effect on CXCR4/CHO-K1 clone 6.

 

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藥靶模型聯(lián)系方式: 華東銷售經(jīng)理(上海):18240630236 華東銷售經(jīng)理(上海、江蘇、安徽):15715191010 華北銷售經(jīng)理:18628311252 華南銷售經(jīng)理:13823536064 華中&華西銷售經(jīng)理:18071545918 華中&西南銷售經(jīng)理:13871580511 全國銷售經(jīng)理:13816461235
診斷標(biāo)準(zhǔn)品聯(lián)系方式: 華東銷售經(jīng)理:15000320447 華北銷售經(jīng)理:18628311252 華南銷售經(jīng)理:13823536064 華中&華西銷售經(jīng)理:18071545918 華中&西南銷售經(jīng)理:13871580511 全國銷售經(jīng)理:13816461235

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